Artichoke is an edible plant that has been used as a court dish as early as ancient Rome and ancient Greece, for the dignitaries to enjoy. Today, the main producing areas of artichokes include Italy, Spain, France, Argentina, and the United States. The edible parts are the internal bracts and receptacles, and the non-edible industrial by-products include the external bracts and stems and leaves, accounting for about 80% of the fresh weight of the whole plant. However, the research on functional active ingredients of artichoke found that its inedible parts, especially the leaves, contain quite a lot of functional substances.
The main active ingredients include polyphenols, flavonoids, terpenoids, etc. It has pharmacological activities such as antioxidant, liver protection, cholesterol lowering, antibacterial, and gastrointestinal improvement. Artichoke Extract UV can be used in food additives, feed additives, antioxidants and even medicines, etc.
What are the proven benefits of Artichoke Extract UV?
1. Artichoke benefits blood pressure regulation
Hypertension is medically defined as a long-term sustained rise in arterial blood pressure above 140/90 Hg mm (systolic blood pressure (SBP)/diastolic blood pressure (DBP)) and can be divided into primary (90%-95%) and secondary (5%-10%), mainly caused by genetics, environment and lifestyle, especially diet.
About 35% of the global population is affected by hypertension, and this proportion may exceed 50% in the future by 2025, with oxidative stress, inflammation, immune regulation and endothelial dysfunction considered as major pathological factors.
Subgroup analyses based on health status and duration of supplementation showed that artichoke administration significantly reduced systolic and diastolic blood pressure in hypertensive patients, and a duration of at least 12 weeks was required to effectively reduce diastolic blood pressure.
Conclusion: Artichoke extract may have positive effects on blood pressure regulation, especially in hypertensive patients, but limited by the small sample size, more research is needed for further verification
2. Antioxidative effect Artichoke leaf extract has antioxidative and protective effects on mouse liver from oxidative stress of hydrogen peroxide, as well as lowering low density lipoprotein (LDL). Using the scavenging effect of each polyphenolic compound isolated from artichoke extract on DPPH free radicals to evaluate their antioxidant capacity, it was found that the antioxidant capacity of polyphenolic compounds was mainly determined by the number of hydroxyl groups on the aromatic ring, The higher the number of hydroxyl groups, the stronger the antioxidant capacity. In addition, the second hydroxyl groups located in the ortho and para positions can also increase its antioxidant capacity.
3. Protect the liver Artichoke root can be used as medicine, has the functions of sterilization, hangover, stimulates bile secretion, etc. It is very effective for liver damage caused by alcohol.
4. Antimicrobial activity Artichoke extract The antimicrobial activity of chlorogenic acid, artichoke acid, luteolin-7-rutinoside and artichoke glycoside is relatively high, and the antifungal activity is stronger than the antibacterial activity. Studies have reported that artichoke leaf extract has obvious resistance to 7 kinds of bacteria, 4 of which are yeasts.
5. Cholesterol-lowering Artichoke extract can regulate human lipid metabolism by reducing cholesterol and endogenous triglycerides in human body. Bile is the main way to eliminate cholesterol, artichoke extract can reduce the cholesterol content in human liver and serum by promoting the secretion of bile. At the same time, there are also many studies showing that artichoke extract can directly act on the synthesis of endogenous cholesterol.
6. Treatment of indigestion The mechanism of artichoke extract in the treatment of indigestion is that it can promote the secretion of bile, and artichoke extract can be used to treat digestive system disorders, accompanied by insufficient bile secretion.
7. Hypolipidemia and anti-atherosclerosis studies have shown that artichoke extract can reduce blood lipids, mainly by affecting the synthesis and decomposition pathways of cholesterol and lipids in the liver to regulate lipid levels. In a double-blind trial, 44 healthy people were randomly divided into groups, and after taking artichoke extract, one group's cholesterol level was significantly lower than the control group. The effect was more pronounced in people with high total cholesterol. However, high-density lipoprotein (HDLS), which is beneficial to health, has a tendency to increase, and can inhibit the oxidation of harmful low-density lipoprotein (LDLS), thereby preventing the occurrence of atherosclerosis.
Safety precautions (6 points of contraindications)
1. Pregnant and lactating women should not use artichoke extract (due to unknown safety).
2. Artichokes belong to the Asteraceae family. People who have been allergic to ragweed, marigold, daisy, chrysanthemum, Echinacea, sunflowers, and other similar herbs may also be allergic to artichokes , should be avoided.
3. Avoid use in patients with gallstones or bile duct obstruction, as artichoke may stimulate the production of bile acids, causing symptoms to worsen
4. The low FODMAP diet or those who are sensitive to FODMAP should be used with caution, because inulin and fructooligosaccharides in artichokes are easily fermented in the small intestine, which can produce gas and cause bloating, weakness, and hunger, especially with heavy use.
5. Do not use in combination with cholesterol-lowering drugs (such as statins/statins), which may affect the efficacy of the drug, because artichoke also has a cholesterol-lowering effect.
6. Do not use with drugs that need to be metabolized by cytochrome P450 (cytochrome P450) enzymes, which may affect the efficacy of the drug.
As a Artichoke Extract UV manufacturers which is specializing in the process, sales and quality control of health care products, such as Super Alpha Lipoic Acid.Creatine Monohydrate Pure Powder.Tribulus Terrestris Extract Powder and so on.Our Ultimate mission is to help customers control the cost of processing and improve the quality of raw materials.Our implant factory has over 10 years of export experience, which supplies high quality productions fully comply with EU regulations.TCL Ingredients Co., Ltd is particularly focusing on manufacturing plant-based pure natural extract powder. These plant extract powder are widely used in the field of health foods, dietary supplements, food, drinks, health care formulation etc. TCL Ingredients Co., Ltd has obtained a series of national and international quality certificates and management qualifications, such as Kosher, Halal and ISO 9001.
