Diosmin Powder is a semi-synthetic flavonoid, a derivative of hesperidin. Used to treat a variety of vascular conditions, including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding in the eyes or gums (bleeding). It is also used to prevent liver toxicity. It is usually mixed with hesperidin.
Mechanism
1. Enhancing venous tension Diosmin enhances venous wall tension, even under high temperature. It causes a stronger venous contraction than other drugs such as rutin, and can still enhance venous tension when the body is in acidosis. Diosmin has a specific affinity for veins without affecting the arterial system.
2. Improve microcirculation diosmin can significantly reduce the adhesion, migration, disintegration of leukocytes and vascular endothelial cells to release inflammatory substances, such as histamine, bradykinin, complement, leukotrienes, prostaglandins and excessive free radicals Diosmin also has the functions of reducing blood viscosity and enhancing the flow rate of red blood cells, thereby reducing microcirculation stasis.
3. Promote lymphatic return Diosmin increases the speed of lymphatic drainage and lymphatic vasoconstriction, thereby accelerating the return of interstitial fluid, improving lymphatic return, and reducing edema.
4. Micronization technology Diosmin adopts a unique micronization technology, which converts drug particles with a diameter of 20 μm into particles with a diameter of only 2 μm, which increases the contact area between the drug and the small intestinal mucosa by 20 times, and the absorption capacity is higher than that of the previous one. Micronized diosmin increased by 4 times, and the clinical efficacy increased by >30%. Oral diosmin 500mg, a single dose of 2 tablets, began to take effect in 1 hour, and the increase in venous tone of patients could be maintained after 1 week of treatment 24h.
In conclusion, diosmin bulk powder is a vascular protection and capillary stabilizer. In the venous system, it can reduce venous distensibility and improve the phenomenon of venous blood stasis. In the microcirculation system, it can normalize the permeability of the capillary wall and enhance its resistance. In clinical practice, diosmin tablets are mainly used to treat venous lymphatic insufficiency related diseases, such as improving leg heaviness, pain, soreness in the morning, etc. symptoms.
When using the drug, it should be noted that it cannot replace the treatment of other anal diseases when used for acute hemorrhoid attacks. If the symptoms cannot be eliminated quickly, a rectal examination should be performed, and the treatment plan should be re-evaluated. In a word, diosmin tablets are drugs with vascular protection and capillary stabilization effects. They are mainly used in the clinical treatment of venous lymphatic insufficiency related diseases, and can also be used for the treatment of acute hemorrhoid attacks.
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