Sodiumhyaluronate is an inherent component in the human body. It is a glucuronic acid with no specific heterogeneity. It widely exists in the placenta, amniotic fluid, lens, articular cartilage, skin dermis and other tissues. In organs, it is distributed in The cytoplasm, the intercellular substance, lubricates and nourishes the cells and organoids contained in it.
At the same time, it provides a microenvironment for cell metabolism. It is a gel made by combining a human body's natural hyaluronic acid with other drugs that promote cell regeneration and wrinkle removal, and is used by injection.
Moisturizing effect is the most important role of sodium hyaluronate in cosmetics. Compared with other moisturizing agents, the relative humidity of the surrounding environment has less influence on its moisturizing ability. Commonly used humectants in cosmetics are glycerin, propylene glycol, sorbitol, polyethylene glycol, sodium lactate, sodium pyrrolidone carboxylate, etc.
In fact, the human body and skin also contain a large amount of hyaluronic acid, which plays a very important role in the process of skin regeneration, metabolism, and aging. It can promote the skin's nutrient metabolism and keep the skin moist, smooth and healthy Elasticity, can also prevent aging, etc., favored by the beauty and skin care industry.
The main sodium hyaluronate skin benefits are as follows:
First, good water absorption and moisturizing effect
Hyaluronic acid has a good moisturizing effect. Hyaluronic acid mainly exists in the dermis in the form of colloid and is mainly responsible for water storage, making the skin look plump and elastic. However, the hyaluronic acid in the human body will gradually disappear with age, causing the skin to lose its ability to store water, gradually darken, age, and form skin wrinkles.
Therefore, skin care products containing hyaluronic acid are essential for anti-aging, moisturizing and moisturizing.
Second, anti-aging
Hyaluronic acid is widely distributed in human connective tissue, and its purity in the vitreous body and joint cavity is very high. It also contains a large amount of hyaluronic acid in the skin, which plays an important role in maintaining the metabolic balance of the skin. If the hyaluronic acid in the skin is damaged, the skin will lose moisture and elasticity, the cells will accelerate aging, and the skin will have wrinkles and spots, so hyaluronic acid is a good anti-aging factor.
Third, skin lubrication and film formation
The aqueous solution of hyaluronic acid has strong viscoelasticity. After being used on the skin surface, it will form a breathable and moisturizing film, making the skin feel moist and elastic. Added to skin care products to thicken and stabilize.
Fourth, the repair and prevention of skin damage
Photoburn or sunburn caused by sun exposure, such as skin reddening, blackening, peeling, etc., is mainly due to the effect of ultraviolet rays in sunlight. Sodium hyaluronate can promote the regeneration of the injured part of the skin by promoting the proliferation and differentiation of epidermal cells and scavenging oxygen free radicals, and prior use also has a certain preventive effect. Its mechanism of action is different from that of UV absorbers commonly used in sunscreens. Therefore, when ha and UV absorbers are used in sunscreen skin care products, they have a synergistic effect and can reduce the penetration of UV rays and the damage caused by a small amount of UV rays. Repair skin damage and play a double protective role
The combination of sodium hyaluronate, egf and heparin can accelerate the regeneration of epidermal cells, making the skin delicate, smooth and elastic. When the skin suffers from mild burns and scalds, applying a water-based cosmetic containing sodium hyaluronate on the surface can relieve pain and accelerate the healing of the injured skin.
Fifth, nutrition
Sodium hyaluronate is an inherent biological substance in the skin, and exogenous sodium hyaluronate supplements the endogenous sodium hyaluronate in the skin. Sodium hyaluronate with a small mass can penetrate into the epidermis layer of the skin to promote the supply of skin nutrients and the excretion of waste, thereby preventing skin aging and playing a role in beauty and beauty. Skin care is more important than other makeup, and it has become the awareness of modern people's desire for beauty.
In summary
1. Although hyaluronic acid has a relatively large molecular weight, various evidences prove that it can be absorbed by the skin when applied to the skin. Therefore, the traditional view that molecules above 500 Da cannot be absorbed is wrong, at least incomplete.
2. Hyaluronic acid not only acts as a moisturizing agent, but can also play a role in absorbing moisture and moisturizing on the skin surface, and may also play a physiologically active role in the skin, such as promoting damage repair and providing cell protection.
3. As an auxiliary substance for transdermal absorption, hyaluronic acid may have certain application value (in addition to the literature cited in this article, there are many papers using hyaluronic acid to make nano-formulations, microspheres, micro-needles, etc. for transdermal delivery and control).
4. After hyaluronic acid is absorbed, it can be completely metabolized and excreted by the body.
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